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Insight into the molecular genetics of myopia – NCBI
by J Li · 2017 · Cited by 51 — Common myopia is usually considered a complex trait because genetic and environmental factors contribute to the susceptibility risk. The genetic …. => Read more
The Molecular Genetics of Human Myopia: An Update – NCBI
by TL Young · 2009 · Cited by 143 — Females are reported to have an earlier onset and a slightly higher prevalence than … This suggests that children inherit myopia as a trait from parents.. => Read more
Genetic and environmental effects on myopia development …
by E Goldschmidt · 2014 · Cited by 135 — The initial approach in genetic research is family studies. … Only three subjects reported the onset of myopia during school years.. => Read more
Myopia Genetics: A Review of Current Research and … – NCBI
by DM Hornbeak · 2009 · Cited by 168 — Most recently, Dirani et al reported the first evidence for a genetic component in adult-onset myopia, within a large cohort study of Caucasian twins.. => Read more
the complex genetics of myopia and refractive error – NCBI
by R Wojciechowski · 2011 · Cited by 337 — Syndromic refractive errors, Several ocular or systemic syndromes with known genetic causes include myopia as a characteristic feature.. => Read more
An overview of myopia genetics – ScienceDirect
by XB Cai · 2019 · Cited by 38 — Genetic characteristics of myopia … Myopia-related phenotypic traits … as an autosomal dominant gene for early-onset high myopia (Ouyang et al., 2019).. => View more
How Environment and Genetics Give Rise to Myopia – Review …
Heritability is the proportion of variation in a trait (myopia) that can be attributed to genetic factors. In fact, the first true twin study of heritability …. => View more
The Genetics of Myopia | SpringerLink
SyndromeGene and inheritance patternOcular phenotype other than m…Beals syndromeFBN2 (AD)Ectopia lentisCornelia de Lange syndromeNIPBL (AD); HDAC8 (XLD)Synophrys, long curly eyelashe…Cowden syndromePTEN (AD)Cataract, angioid streaksView 78 more rows. => View more
IMI – Myopia Genetics Report | IOVS
by MS Tedja · 2019 · Cited by 88 — It is clear that the trait is complex, with many genetic variants of small … genes in early-onset high myopia in 298 unrelated myopia probands and their …. => View more
FAQ: “Early onset myopia as an inherited trait?”
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Answer: “Early onset myopia as an inherited trait?”
Short-sightedness is known to run in families, so you’re more likely to develop it if one or both or your parents are also short-sighted. Research has so far identified more than 40 genes linked to short-sightedness.
2003; Pararajasegaram 1999). High myopia is usually regarded as hereditary—as an autosomal dominant, autosomal recessive, or X-linked recessive trait. Some high myopia might be inherited in a complex fashion. So far, eight loci for high myopia have been reported, including MYP1 (Xq28) (Young et al.
Large family studies have reported heritability of refractive error to be 50% to 60%, and a meta-analysis of both twin and family studies suggest a myopia heritability of about 71%. Genetic linkage studies.
Ohad Birk has identified a gene whose defect specifically causes myopia or nearsightedness. In an article appearing online in the American Journal of Human Genetics, Birk and his team reveal that a mutation in LEPREL1 has been shown to cause myopia.Can myopia be inherited?
Is myopia a dominant or recessive trait?
How much of myopia is genetic?
What gene is responsible for myopia?Short-sightedness (myopia) – Causes – NHS
Confirmation of a genetic locus for X-linked recessive high myopia …
How Environment and Genetics Give Rise to Myopia – Review …
Researchers identify gene that leads to myopia (nearsightedness)
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